The Frederick Hill Meserve Collection comprises more than five thousand Civil War-era portrait negatives from the Mathew Brady photography studio in New York City. The collection, which the National Portrait Gallery acquired in 1981, includes portraits of generals, politicians, diplomats, painters, and performers. It also contains depictions of “Human Curiosities” at P. T. Barnum’s American Museum in New York City, that, although highly exploitative, help to document the historical representations of disability in the United States.